Peptide Database

Peptide NameDefb14-1CV(13-34)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Standard StatusStandard

Sequence Length22 amino acids

Chemical FormulaC95H168N34O30

DescriptionStandard

        IRGGRAAVLNALGKEEQIGRAS
    

Molecular Weight2266.56 Da

Isoelectric Point (pI)10.74

Net Charge (pH 7.0)1.76

Net Charge (pH 7.4) 1.56

Charge Density (pH 7.0) 0.0802

GRAVY Index-0.26

Hydrophobic Moment 0.44

Boman Index-0.09

Instability Index31.01

Aliphatic Index 102.27

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1067.15

LogP -13.19

H-bond Donors 38.0

H-bond Acceptors 32.0

Rotatable Bonds 80.0

Heavy Atoms 159.0

Ring Count 0.0

Amide Bonds 23.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0384353 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyDefensin

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetMonomer: [Pseudomonas aeruginosa PAO1

Activity22 μM

MethodMIC