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MYP_145283
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Basic Information
Temporin-Las
Anticancer
Antimicrobial
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Standard
13 amino acids
C76H132N20O16
Standard
Sequence
LLRHVVKILSKYL
Physicochemical Analysis
1581.99 Da
10.29
2.84
2.59
0.2188
0.81
0.79
0.15
44.93
194.62
0.0769
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
595.60
-0.81
22.0
20.0
54.0
112.0
2.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0211494 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
MEC
27.99 %
Cell proliferation inhibition assay (50 μg/mL peptide exposure)
PaperPubMed PMID: 22641352 PMID22641352 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22641352/
RECORD: Rec_0222008 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
Cancer cell lines tested in PMID 22641352
Cell proliferation inhibition assay
PaperPubMed PMID: 22641352 PMID22641352 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22641352/
RECORD: Rec_0261631 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer
HEK-293T
Cell proliferation inhibition assay (50 μg/mL peptide exposure)
PMID22641352 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22641352/
RECORD: Rec_0264025 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporins
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer
HepG-2 (liver cancer)
Cell proliferation inhibition assay (50 μg/mL peptide exposure)
PaperDesigned synthetic analogs of the α-helical peptide temporin-La with improved antitumor efficacies via charge modification and incorporation of the integrin αvβ3 homing domain | https://pubmed.ncbi.nlm.nih.gov/22641352/ PMID22641352 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22641352/
RECORD: Rec_0268479 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporins
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer
MEC (breast cancer)
Cell proliferation inhibition assay (50 μg/mL peptide exposure)
PaperDesigned synthetic analogs of the α-helical peptide temporin-La with improved antitumor efficacies via charge modification and incorporation of the integrin αvβ3 homing domain | https://pubmed.ncbi.nlm.nih.gov/22641352/ PMID22641352 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22641352/
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