Peptide Database

Peptide NameBeta-defensin 1TB

Function Ontology

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Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC166H252N46O47S7

DescriptionStandard

        DHYQCVRNGGFCLYSACPMFSKIVGTCYNGKAKCC
    

Molecular Weight3868.51 Da

Isoelectric Point (pI)8.64

Net Charge (pH 7.0)2.78

Net Charge (pH 7.4) 2.43

Charge Density (pH 7.0) 0.0795

GRAVY Index0.00

Hydrophobic Moment 0.45

Boman Index0.06

Instability Index25.70

Aliphatic Index 44.57

Aromaticity 0.1429

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1500.52

LogP -16.51

H-bond Donors 58.0

H-bond Acceptors 58.0

Rotatable Bonds 123.0

Heavy Atoms 266.0

Ring Count 7.0

Amide Bonds 37.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0152148 VERIFIED: YES

Provenance & Taxonomy

OrganismChinchilla lanigera [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)