Peptide Database

Peptide NameProlactin-releasing peptide PrRP20

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Regulatory peptide ▸ Cell-cell communication

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC104H157N31O27

DescriptionStandard

        TPDINPAWYASRGIRPVGRF
    

Molecular Weight2273.55 Da

Isoelectric Point (pI)10.74

Net Charge (pH 7.0)1.40

Net Charge (pH 7.4) 1.21

Charge Density (pH 7.0) 0.0699

GRAVY Index-0.51

Hydrophobic Moment 0.92

Boman Index-0.04

Instability Index41.91

Aliphatic Index 63.50

Aromaticity 0.1500

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 932.42

LogP -8.39

H-bond Donors 33.0

H-bond Acceptors 29.0

Rotatable Bonds 65.0

Heavy Atoms 162.0

Ring Count 7.0

Amide Bonds 20.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0012452 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyProlactin-releasing peptide PrRP20

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator Metabolic regulation Physiological regulation Growth regulation Development regulation Receptor modulation Feeding regulator

Half-LifeMammalian: 7.2 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0278879 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyFMRFamide related peptide

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

RFamide Neuropeptide Neuromodulator

RECORD: Rec_0284294 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide; DSSP H 0.0%, E 10.0%, T 50.0%, C 40.0% [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Cell-Cell Communication

RECORD: Rec_0375162 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Hormone

TargetGPR10