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MYP_145219
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Basic Information
Unnamed
Antimicrobial
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Venom / Toxin ▸ General toxin ▸ Toxin
Standard
9 amino acids
C56H84N14O13
Standard
Sequence
LVVYPWTQR
Physicochemical Analysis
1161.35 Da
8.75
0.76
0.55
0.0843
-0.03
0.23
0.11
-14.06
107.78
0.2222
6990.00
6990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
448.57
-1.28
16.0
14.0
32.0
83.0
4.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0137006 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Hemorphin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
0 μM
IC50
PaperHemorfins derived from hemoglobin have an inhibitory action on angiotensin converting enzyme activity
RECORD: Rec_0157034 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Hemorphin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Opioid
opioid receptor
PaperGl?msta E. L., Marklund A., Hellmann U., Wernstedt C., Terenius L., Nyberg F.. Isolation and characterization of a hemoglobin-derived opioid peptide from the human pituitary gland. Regulatory Peptides, 34, 169-179, 1991.
RECORD: Rec_0158246 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Hemorphin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
PaperLantz I., Gl?msta E.-L., T?lback L., Nyberg F.. Hemorphins derived from hemoglobin have an inhibitory action on angiotensin-converting enzyme activity. FEBS Lett., 287, 39-41, 1991.
RECORD: Rec_0216713 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antihypertensive
PaperAHTPDB: a comprehensive platform for analysis and presentation of antihypertensive peptides PMID25392419 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25392419/
RECORD: Rec_0228881 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal] [Animal]; Bos taurus [Animal] [Animal]; Rattus norvegicus [Animal]
9606;9913;10116
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide Enzyme inhibitory Toxin
90.0 μM
IC50
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