Peptide Database

Peptide NameGloba F

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length31 amino acids

Chemical FormulaC138H218N36O41S6

DescriptionStandard

        GSFPCGESCVFIPCISAIAGCSCKNKVCYKN
    

Molecular Weight3229.81 Da

Isoelectric Point (pI)8.33

Net Charge (pH 7.0)1.70

Net Charge (pH 7.4) 1.40

Charge Density (pH 7.0) 0.0548

GRAVY Index0.48

Hydrophobic Moment 0.28

Boman Index0.20

Instability Index37.38

Aliphatic Index 62.90

Aromaticity 0.0968

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1221.43

LogP -14.68

H-bond Donors 47.0

H-bond Acceptors 49.0

Rotatable Bonds 102.0

Heavy Atoms 221.0

Ring Count 5.0

Amide Bonds 32.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0148499 VERIFIED: YES

Provenance & Taxonomy

OrganismGloeospermum blakeanum [Plant]

FamilyCyclotide

Structure & Mods

Confighead-to-tail cyclic peptide scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

DisulfideCysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family

Bio-Activity Profile

Function

Enzymatic-digestion

RECORD: Rec_0257676 VERIFIED: YES

Provenance & Taxonomy

OrganismGloeospermum blakeanum [Plant]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)