Peptide Database

Peptide NameHNHc domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length686 amino acids

Chemical FormulaC3273H5277N953O1010S14

DescriptionStandard

        MSGGDGRDHNSGAHDSGGAINGGPTGIGGNGGSTSGGSGSGSGWGISNTPYGNIYHYDPDKFGGKKGNEGGDSGSPKDSVDLSKTLNNVTMAGFPMSGYMVEGVLGFSIAASALMAMGKDMLAAIGVLIGRFTPLAGRVLGLPSLLIPSQIEPDPPMNIHIKNLDAIDKENPYSYVMLNSDLVTTVPADKIPGNTSVPARMLAQAVIDDIEKSRPVAITPVESTPVPVVKAQRTDKRNVYTAQVVPGMKPMRIKIDNSRAVKPAPAPVKPDSLPAPKQYLPAPKEKDNTSHHAIIDFGGDHAPVYVSVTKEVKPEEAKKLAEKARKEWVADNPAGVSQLLADINILIAARNKQLAEKQQALKSKQAEFQAFLDKYQHAIPFVKRGVNFSAREHTFKAEISQINADISGIQKELTDAAGNKALNEKTLAELNEQERNQTKTLEDAENELAAADAALSKARALVTETEKQLAAKRQALNNKQVEFQAFLDKYQRAIPFVKRGINFKGKERDFQAAIGQLSTEVGQQEKVLADAMESRKKAEGKKKTTEDKVRTKRDEKRKQPGTATGKGQKVGDKWLEDAGKESGVPIPDRIADKLRGKKFNNFDDFRKKFWEEVSKDPELLKQFGNQNKTNIKNGKAPFARKKDRSGGRERFELHHDKPISEGGGVYDMDNLRVTTPKRHIDIHRGK
    

Molecular Weight74586.60 Da

Isoelectric Point (pI)9.40

Net Charge (pH 7.0)18.72

Net Charge (pH 7.4) 17.61

Charge Density (pH 7.0) 0.0273

GRAVY Index-0.68

Hydrophobic Moment 0.77

Boman Index-0.11

Instability Index37.02

Aliphatic Index 72.30

Aromaticity 0.0554

Extinction Coeff. Reduced 39880.00

Extinction Coeff. Oxidized 39880.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0110562 VERIFIED: NO

Provenance & Taxonomy

OrganismMorganella morganii [Bacterium]

FamilyColicin/Pyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Hydrolase Non-hemolytic Non-ribosomal

TargetEscherichia coli

MethodQualitative functional evidence