Peptide Database

Peptide NameEosinophil Cationic Protein (RNase 3)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium

Standard StatusStandard

Sequence Length70 amino acids

Chemical FormulaC360H566N120O96S5

DescriptionStandard

        RPPQFTRAQWFAIQHISLNPPRCTIAMRAINNYRWRCKNQNTFLRTTFANVVNVCGNQSIRCPHNRTLNN
    

Molecular Weight8271.42 Da

Isoelectric Point (pI)11.71

Net Charge (pH 7.0)9.89

Net Charge (pH 7.4) 9.53

Charge Density (pH 7.0) 0.1413

GRAVY Index-0.65

Hydrophobic Moment 0.50

Boman Index-0.18

Instability Index48.03

Aliphatic Index 64.14

Aromaticity 0.1000

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3570.84

LogP -42.06

H-bond Donors 127.0

H-bond Acceptors 113.0

Rotatable Bonds 263.0

Heavy Atoms 581.0

Ring Count 16.0

Amide Bonds 85.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0069657 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyNatural peptide

Tax ID9606

Structure & Mods

Configcyclic peptide [Cyclic]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermNone

C-TermNone

DisulfideDisulfide linkage reported

Bio-Activity Profile

Function

Antimicrobial Antimycobacterial Antibacterial

TargetMycobacterium vaccae strain (ATCC 15483)

Activity0.2 μM

MethodIC50

RECORD: Rec_0343898 VERIFIED: YES