Peptide Database

Peptide NameU-poneritoxin(01)-Om4a (U-PONTX(01)-Om4a) (Pilosulin-like peptide 4) (PLP4) (Poneratoxin)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Standard StatusStandard

Sequence Length68 amino acids

Chemical FormulaC337H533N81O90S5

DescriptionStandard

        MKPSSLTLAFLVVFMMAIMYNSVQAEALADADAEAFAEAGVKELFGKAWGLVKKHLPKACGLLGYVKQ
    

Molecular Weight7319.65 Da

Isoelectric Point (pI)7.87

Net Charge (pH 7.0)0.58

Net Charge (pH 7.4) 0.28

Charge Density (pH 7.0) 0.0086

GRAVY Index0.49

Hydrophobic Moment 0.48

Boman Index0.26

Instability Index24.26

Aliphatic Index 100.59

Aromaticity 0.1029

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2696.50

LogP -16.74

H-bond Donors 92.0

H-bond Acceptors 97.0

Rotatable Bonds 244.0

Heavy Atoms 513.0

Ring Count 11.0

Amide Bonds 70.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0157518 VERIFIED: YES

Provenance & Taxonomy

OrganismOdontomachus monticola [Animal]

FamilyFormicidae venom precursor-01

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antifungal Anti-Yeast Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic

TargetEscherichia coli (Gram-negative)

RECORD: Rec_0274530 VERIFIED: YES

Provenance & Taxonomy

OrganismOdontomachus monticola [Animal]

FamilyFormicidae venom precursor-01

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antifungal Anti-Yeast Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic

TargetS. cerevisiae

RECORD: Rec_0295369 VERIFIED: YES

Provenance & Taxonomy

OrganismOdontomachus monticola [Animal]

FamilyFormicidae venom precursor-01

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antifungal Anti-Yeast Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic

TargetStaphylococcus aureus (Gram-positive)