Peptide Database

Peptide NameCyclo(His-Phe)

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Enzyme modulation ▸ Enzyme inhibition ▸ DPP-III Inhibitory

Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory

Metabolic ▸ Glucose metabolism ▸ Antidiabetic

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length2 amino acids

Chemical FormulaC15H18N4O3

DescriptionStandard

HF

Molecular Weight302.33 Da

Isoelectric Point (pI)6.74

Net Charge (pH 7.0)-0.15

Net Charge (pH 7.4) -0.41

Charge Density (pH 7.0) -0.0764

GRAVY Index-0.20

Hydrophobic Moment 0.66

Boman Index0.40

Instability Index-46.85

Aliphatic Index 0.00

Aromaticity 0.5000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 121.10

LogP 0.09

H-bond Donors 4.0

H-bond Acceptors 4.0

Rotatable Bonds 7.0

Heavy Atoms 22.0

Ring Count 2.0

Amide Bonds 1.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0336919 VERIFIED: YES

Provenance & Taxonomy

OrganismCapra hircus [Animal]

Tax ID9925.0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

DPP-III Inhibitory

TargetDipeptidyl peptidase III

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