Peptide Database

Peptide NameFrenatin 4.1 [Cleaved into: Frenatin 4.2]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length70 amino acids

Chemical FormulaC355H571N89O112S2

DescriptionStandard

        MAFLKKSLFLVLFLGLVNLSICEEEKREEENKEEEDENEALSEVKRGFLEKLKTGAKDFASAFVNSIKGT
    

Molecular Weight7941.99 Da

Isoelectric Point (pI)4.85

Net Charge (pH 7.0)-4.48

Net Charge (pH 7.4) -4.75

Charge Density (pH 7.0) -0.0640

GRAVY Index-0.34

Hydrophobic Moment 0.65

Boman Index-0.05

Instability Index45.36

Aliphatic Index 90.57

Aromaticity 0.0857

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3302.67

LogP -28.11

H-bond Donors 113.0

H-bond Acceptors 110.0

Rotatable Bonds 285.0

Heavy Atoms 558.0

Ring Count 6.0

Amide Bonds 73.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0310239 VERIFIED: YES

Provenance & Taxonomy

OrganismNyctimystes infrafrenatus [Animal]

FamilyFrog skin active peptide (FSAP); Frenatin subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Gram-negative Hemolytic

TargetEscherichia coli (Gram-negative)

RECORD: Rec_0345090 VERIFIED: YES