Peptide Database

Peptide NameHuman islet amyloid polypeptide

Function Ontology

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Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC172H265N49O54S2

DescriptionStandard

        KCNTVTCATQRLANFLIHSSNNFGAIFSPPSVGSNSY
    

Molecular Weight3947.37 Da

Isoelectric Point (pI)8.90

Net Charge (pH 7.0)1.83

Net Charge (pH 7.4) 1.54

Charge Density (pH 7.0) 0.0493

GRAVY Index-0.03

Hydrophobic Moment 0.48

Boman Index0.11

Instability Index21.22

Aliphatic Index 65.95

Aromaticity 0.1081

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1670.78

LogP -23.68

H-bond Donors 59.0

H-bond Acceptors 59.0

Rotatable Bonds 123.0

Heavy Atoms 277.0

Ring Count 7.0

Amide Bonds 42.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0360723 VERIFIED: YES

Provenance & Taxonomy

OrganismOryctolagus cuniculus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)