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MYP_144948
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Basic Information
[T8A]-Penaeidin-3a ([T8A]-Pen-3a; shrimps, Arthropods, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
63 amino acids
C292H457N91O77S6
Standard
Sequence
QVYKGGYARPIPRPPPFVRPLPGGPIGPYNGCPVSCRGISFSQARSCCSRLGRCCHVGKGYSG
Physicochemical Analysis
6666.71 Da
9.89
8.78
8.43
0.1394
-0.34
0.66
-0.02
56.43
52.54
0.0952
5960.00
6335.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2625.21
-31.36
97.0
93.0
199.0
466.0
17.0
65.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0033585 VERIFIED: YES
Provenance & Taxonomy
Litopenaeus vannamei [Animal]
Penaeidin
6689
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Pyroglutamate
Amidation
32-47, 36-54, 48-55
O-glycosylated on Thr8
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Fusarium oxysporum
3.12-6.25 μM
MIC
PMID12842879 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12842879/
RECORD: Rec_0063751 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Penaeidin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Salmonella thyphimurium
50 μM
MIC
PMID12842879 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12842879/
RECORD: Rec_0064711 VERIFIED: YES
Provenance & Taxonomy
Litopenaeus vannamei [Animal]
Penaeidin
6689
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Pyroglutamate
Amidation
32-47, 36-54, 48-55
O-glycosylated on Thr8
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Aerococcus viridans
0.4-0.8 μM
MIC
PMID12842879 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12842879/
RECORD: Rec_0102337 VERIFIED: YES
Provenance & Taxonomy
Litopenaeus vannamei [Animal]
Penaeidin
6689
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Pyroglutamate
Amidation
32-47, 36-54, 48-55
O-glycosylated on Thr8
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Escherichia coli 363 (MI=3.12-6.25 μM)
PMID12842879 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12842879/
RECORD: Rec_0120841 VERIFIED: YES
Provenance & Taxonomy
Litopenaeus vannamei [Animal]
Penaeidin
6689
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Pyroglutamate
Amidation
32-47, 36-54, 48-55
O-glycosylated on Thr8
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Micrococcus luteus
0.8-1.6 μM
MIC
PMID12842879 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12842879/
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