Peptide Database

Peptide NameCircularin A uberolysin family circular bacteriocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length107 amino acids

Chemical FormulaC510H814N126O139S2

DescriptionStandard

        MTYSVKGRAVSFGALLAVGGALLASYAFLLGILPEMNLVKEFNLSTVAAAQVFAWLDYISWGVSLVALIGSLGTGGASLVAAAGAQGIRKYLTDLAKEKGKKAAIAY
    

Molecular Weight10998.81 Da

Isoelectric Point (pI)9.52

Net Charge (pH 7.0)3.50

Net Charge (pH 7.4) 3.26

Charge Density (pH 7.0) 0.0327

GRAVY Index0.75

Hydrophobic Moment 0.66

Boman Index0.34

Instability Index8.80

Aliphatic Index 119.63

Aromaticity 0.1028

Extinction Coeff. Reduced 18450.00

Extinction Coeff. Oxidized 18450.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4179.42

LogP -32.85

H-bond Donors 148.0

H-bond Acceptors 145.0

Rotatable Bonds 362.0

Heavy Atoms 777.0

Ring Count 14.0

Amide Bonds 110.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0007250 VERIFIED: NO

Provenance & Taxonomy

OrganismBacillus thuringiensis [Bacterium]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

RECORD: Rec_0078427 VERIFIED: NO

Provenance & Taxonomy

OrganismBacillus thuringiensis Bt18247 [Bacterium]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

RECORD: Rec_0184794 VERIFIED: NO

Provenance & Taxonomy

OrganismBacillus cereus [Bacterium]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

RECORD: Rec_0232945 VERIFIED: NO

Provenance & Taxonomy

OrganismBacillus thuringiensis subsp. kyushuensis [Bacterium]

FamilyCircular bacteriocin

Structure & Mods

Configcyclic peptide topology reported [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

RECORD: Rec_0266368 VERIFIED: NO

Provenance & Taxonomy

OrganismBacillus thuringiensis DB27 [Bacterium]

FamilyBacteriocin

Tax ID1431339

Structure & Mods

Confighead-to-tail cyclic peptide [Cyclic]

Chiralitynoncanonical stereochemical modification [Modified]

Other ModsCyclized peptide scaffold annotation

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Non-hemolytic Non-ribosomal