Peptide Database

Peptide NameCircular bacteriocin; circularin A uberolysin family

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length72 amino acids

Chemical FormulaC332H558N88O92S4

DescriptionStandard

        MIELTMELMNSMNIGRSTATHVIDLAVAGASAWAIVASIAAGGGIIAIGAVAVRTLIKSKLKKLGYTALVAW
    

Molecular Weight7382.78 Da

Isoelectric Point (pI)9.82

Net Charge (pH 7.0)2.59

Net Charge (pH 7.4) 2.31

Charge Density (pH 7.0) 0.0360

GRAVY Index0.92

Hydrophobic Moment 0.47

Boman Index0.36

Instability Index17.72

Aliphatic Index 130.28

Aromaticity 0.0417

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2838.17

LogP -23.57

H-bond Donors 102.0

H-bond Acceptors 100.0

Rotatable Bonds 247.0

Heavy Atoms 516.0

Ring Count 6.0

Amide Bonds 73.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0293673 VERIFIED: NO

Provenance & Taxonomy

OrganismCarnobacterium sp. [Bacterium]

FamilyBacteriocin

Tax ID48221

Structure & Mods

Confighead-to-tail cyclic bacteriocin scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsCyclized peptide scaffold annotation

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Non-hemolytic Non-ribosomal