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MYP_144926
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Basic Information
BPC200
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Standard
10 amino acids
C62H110N14O12
Standard
Sequence
LLLLKFKKLQ
Physicochemical Analysis
1243.62 Da
10.30
2.76
2.55
0.2757
0.66
0.27
0.11
9.59
195.00
0.1000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
446.37
0.89
15.0
15.0
46.0
88.0
1.0
10.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0046972 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
MDA-MB-231 human breast adenocarcinoma cells
11±0.27 % growth inhibition
Cell growth-inhibition assay
PMID20708052 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20708052/
RECORD: Rec_0116566 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Erwinia amylovora PMV 6076
100 μM
MIC
PMID20708052 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20708052/
RECORD: Rec_0163089 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
Xanthomonas vesicatoria; Pseudomonas syringae; Erwinia amylovora; MDA-MB-231 cells; human erythrocytes
MIC; Cell growth-inhibition assay; Hemolysis
PaperAntimicrobial cyclic decapeptides with anticancer activity. Peptides. 2010 Nov;31(11):2017-26. doi: 10.1016/j.peptides.2010.07.027. PMID: 20708052. PMID20708052 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20708052/
RECORD: Rec_0167017 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Xanthomonas vesicatoria 2133-2
12.5-25 μM
MIC
PMID20708052 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20708052/
RECORD: Rec_0259190 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
head-to-tail cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas syringae pv. syringae EPS 94
25-50 μM
MIC
PMID20708052 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20708052/
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