Peptide Database

Peptide NameMra14a

Function Ontology

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Standard StatusStandard

Sequence Length31 amino acids

Chemical FormulaC136H222N36O42S6

DescriptionStandard

        GSIPCGESCVFIPCISSVVGCSCKNKVCYKN
    

Molecular Weight3225.82 Da

Isoelectric Point (pI)8.33

Net Charge (pH 7.0)1.70

Net Charge (pH 7.4) 1.40

Charge Density (pH 7.0) 0.0548

GRAVY Index0.52

Hydrophobic Moment 0.35

Boman Index0.18

Instability Index33.71

Aliphatic Index 75.16

Aromaticity 0.0645

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1241.66

LogP -15.65

H-bond Donors 48.0

H-bond Acceptors 50.0

Rotatable Bonds 103.0

Heavy Atoms 220.0

Ring Count 4.0

Amide Bonds 32.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0094848 VERIFIED: YES

Provenance & Taxonomy

OrganismMelicytus ramiflorus [Plant]

FamilyCyclotide

Tax ID344147

Structure & Mods

Confighead-to-tail cyclic peptide scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

DisulfideCysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family

Bio-Activity Profile

Function

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RECORD: Rec_0196855 VERIFIED: YES

Provenance & Taxonomy

OrganismMelicytus ramiflorus [Plant]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)