Peptide Database

Peptide NameFMRFamide-9

Function Ontology

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length8 amino acids

Chemical FormulaC41H69N13O10S

DescriptionStandard

        AKGNLMRF
    

Molecular Weight936.13 Da

Isoelectric Point (pI)11.00

Net Charge (pH 7.0)1.79

Net Charge (pH 7.4) 1.61

Charge Density (pH 7.0) 0.2244

GRAVY Index-0.25

Hydrophobic Moment 0.42

Boman Index-0.10

Instability Index-21.90

Aliphatic Index 61.25

Aromaticity 0.1250

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 398.03

LogP -3.25

H-bond Donors 14.0

H-bond Acceptors 13.0

Rotatable Bonds 32.0

Heavy Atoms 65.0

Ring Count 1.0

Amide Bonds 8.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0024378 VERIFIED: YES

Provenance & Taxonomy

OrganismAedes aegypti [Animal]

FamilyFMRFamide related peptide

Tax ID7159

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

RFamide Neuropeptide Neuromodulator

RECORD: Rec_0085856 VERIFIED: YES

Provenance & Taxonomy

OrganismAedes aegypti [Animal]

FamilyFMRFamide

Tax ID7159

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide Neuromodulator

Half-LifeMammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0184151 VERIFIED: NO

Provenance & Taxonomy

OrganismAedes aegypti [Animal]

Tax ID7159

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide

RECORD: Rec_0234007 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/