Peptide Database

Peptide NamePG 99-465

Function Ontology

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length31 amino acids

Chemical FormulaC157H257N45O46S

DescriptionStandard

        HSDAVFTDNYTKLRKQMAVKKYLNSIKKGGT
    

Molecular Weight3543.06 Da

Isoelectric Point (pI)10.00

Net Charge (pH 7.0)4.84

Net Charge (pH 7.4) 4.57

Charge Density (pH 7.0) 0.1562

GRAVY Index-0.87

Hydrophobic Moment 0.70

Boman Index-0.21

Instability Index16.85

Aliphatic Index 62.90

Aromaticity 0.0968

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1528.50

LogP -16.32

H-bond Donors 54.0

H-bond Acceptors 53.0

Rotatable Bonds 124.0

Heavy Atoms 249.0

Ring Count 4.0

Amide Bonds 33.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0165606 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Receptor agonist Signaling peptide

TargetPAC1 receptor (Human); VPAC1 receptor (Human); VPAC2 receptor (Human)

Activity71.3 nM

MethodEC50