Peptide Database

Peptide NameBeta-defensin 1TB

Function Ontology

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Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC163H253N47O48S6

DescriptionStandard

        DHYICARKGGTCNFSPCPLFTRIEGTCYSGKAKCC
    

Molecular Weight3831.43 Da

Isoelectric Point (pI)8.65

Net Charge (pH 7.0)2.79

Net Charge (pH 7.4) 2.44

Charge Density (pH 7.0) 0.0796

GRAVY Index-0.24

Hydrophobic Moment 0.37

Boman Index-0.03

Instability Index40.25

Aliphatic Index 39.14

Aromaticity 0.1143

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1524.98

LogP -18.22

H-bond Donors 60.0

H-bond Acceptors 58.0

Rotatable Bonds 121.0

Heavy Atoms 264.0

Ring Count 7.0

Amide Bonds 35.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0399648 VERIFIED: YES

Provenance & Taxonomy

OrganismManis javanica [Animal]

FamilyDefensin

Structure & Mods

ConfigDNA-encoded linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)