Peptide Database

Peptide NameCycloviolacin O5

Function Ontology

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Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC130H205N35O38S6

DescriptionStandard

        PCGESCVFIPCISSFLGCSCKNKVCYRN
    

Molecular Weight3058.62 Da

Isoelectric Point (pI)8.46

Net Charge (pH 7.0)1.90

Net Charge (pH 7.4) 1.75

Charge Density (pH 7.0) 0.0678

GRAVY Index0.38

Hydrophobic Moment 0.36

Boman Index0.11

Instability Index38.68

Aliphatic Index 62.50

Aromaticity 0.1071

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1164.81

LogP -13.75

H-bond Donors 47.0

H-bond Acceptors 46.0

Rotatable Bonds 97.0

Heavy Atoms 209.0

Ring Count 5.0

Amide Bonds 29.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0289420 VERIFIED: YES

Provenance & Taxonomy

OrganismPombalia lanata [Plant]

FamilyCyclotide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)