MYP_144825
semaglutide
Hormonal / Endocrine
▸
Hormone peptide
Metabolic
▸
Glucose metabolism
▸
Antidiabetic
▸
Standard
36 amino acids
C174H265N49O57S3
Standard
HDEFERHALPHAAMINISTYRICACIDEGTFTSDVS
4051.45 Da
4.89
-3.99
-4.38
-0.1108
-0.14
0.44
0.05
41.21
73.33
0.0833
1490.00
1615.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
1691.37
-18.05
61.0
59.0
129.0
283.0
7.0
36.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0087176
VERIFIED: YES
Provenance & Taxonomy
not reported [other]
GLP-1
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
Amidation
Acylation of peptide at K-26 with C-18 fatty di-acid chain
Bio-Activity Profile
Anti-diabetic
Insulin secretion stimulation
<0.002 μM
ED50
Mini-pigs plasma (Dose s/c injected), in vivo; 165600 s
RECORD: Rec_0281100
VERIFIED: YES
Provenance & Taxonomy
not reported [other]
GLP-1
Structure & Mods
linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
Amidation
Alpha-aminoisobutyric acid at 8th position, Acylation of peptide at K-26 with C-18 fatty di-acid chain
Bio-Activity Profile
Anti-diabetic
Insulin secretion stimulation
<0.002 μM
ED50
Human plasma (Dose s/c injected), in vivo; 594000 s