Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length228 amino acids

Chemical FormulaC1160H1767N265O344S8

DescriptionStandard

        IDDLAEVDYSLNSLPAVFRPFIDLDLKGIVYPAGNHTGPPYVAAPFTIPDQSDSMLYLAFSEYFFQTSSFAYYTARAFDITIAEETCSYFNISTEIFGSIIPEVAKYSVAPYPVMLKLMATEIPVISLEQDSFTVEIQGSMEVFAVLPDSTTQSLFTMNIAANTSIALNIFDQKLMGSLCLNRLQFSLAHSNVGFFEISLLENILSYILQTEVIPSANAKLSKGFPLP
    

Molecular Weight25185.53 Da

Isoelectric Point (pI)4.20

Net Charge (pH 7.0)-15.05

Net Charge (pH 7.4) -15.44

Charge Density (pH 7.0) -0.0660

GRAVY Index0.34

Hydrophobic Moment 0.60

Boman Index0.25

Instability Index48.12

Aliphatic Index 100.57

Aromaticity 0.1272

Extinction Coeff. Reduced 16390.00

Extinction Coeff. Oxidized 16515.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0281745 VERIFIED: NO

Provenance & Taxonomy

OrganismAramus guarauna (Limpkin) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria