Peptide Database

Peptide NameDs-defensin

Function Ontology

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Standard StatusStandard

Sequence Length41 amino acids

Chemical FormulaC197H309N71O51S6

DescriptionStandard

        VEAGFGCPFNQGRCHRHCRSIGRRGGYCRGIFKQTCACYRK
    

Molecular Weight4680.40 Da

Isoelectric Point (pI)9.86

Net Charge (pH 7.0)7.85

Net Charge (pH 7.4) 7.44

Charge Density (pH 7.0) 0.1914

GRAVY Index-0.68

Hydrophobic Moment 0.85

Boman Index-0.26

Instability Index58.07

Aliphatic Index 30.98

Aromaticity 0.1220

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2008.72

LogP -24.62

H-bond Donors 80.0

H-bond Acceptors 67.0

Rotatable Bonds 154.0

Heavy Atoms 325.0

Ring Count 8.0

Amide Bonds 43.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0345724 VERIFIED: YES

Provenance & Taxonomy

OrganismAndroctonus bicolor [Animal]

FamilyDefensin

Structure & Mods

ConfigDNA-encoded linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)