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MYP_144807
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Basic Information
CXCL10
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Antiviral
Binding / Molecular interaction ▸ Binding activity
Immunology ▸ Chemokine signaling ▸ Chemokine-like peptide
Immunology ▸ Immune modulation ▸ Cytokine modulation
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity
Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Angiogenic
Standard
77 amino acids
C375H652N114O108S5
Standard
Sequence
VPLSRTVRCTCISISNQPVNPRSLEKLEIIPASQFCPRVEIIATMKKKGEKRCLNPESKAIKNLLKAVSKERSKRSP
Physicochemical Analysis
8646.21 Da
10.20
10.70
10.41
0.1390
-0.47
0.75
-0.20
64.74
89.87
0.0130
0.00
250.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
3631.99
-39.48
130.0
124.0
298.0
602.0
8.0
82.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0117735 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC29213
PMID12949249 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12949249/
RECORD: Rec_0164112 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC25922
PMID12949249 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12949249/
RECORD: Rec_0278530 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Defensin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antiparasitic
Pseudomonas aeruginosa, Listeria monocytogenes
7 μg/mL
MIC
PaperCutting edge: IFN-inducible ELR- CXC chemokines display defensin-like antimicrobial activity.
RECORD: Rec_0281391 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Defensin
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antiparasitic
Escherichia coli
3.6 μg/mL
MIC
PaperCutting edge: IFN-inducible ELR- CXC chemokines display defensin-like antimicrobial activity.
RECORD: Rec_0397379 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic
PaperPubMed PMID: 12949249 | PubMed PMID: 12737818 PMID12949249;12737818 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12949249/
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