Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC483H769N131O140S9

DescriptionStandard

        MKILCIFLTFVFTVSCGPSVSQKKTKEDVDRKRECYLVRGACKTSCNSWEYIYNYCNTEPCCVVRDYQKPVTKHITTSSYRVNDKSTIPHKIKL
    

Molecular Weight10939.65 Da

Isoelectric Point (pI)9.17

Net Charge (pH 7.0)7.59

Net Charge (pH 7.4) 7.13

Charge Density (pH 7.0) 0.0808

GRAVY Index-0.40

Hydrophobic Moment 0.69

Boman Index-0.11

Instability Index39.50

Aliphatic Index 70.32

Aromaticity 0.1064

Extinction Coeff. Reduced 14440.00

Extinction Coeff. Oxidized 14940.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4425.56

LogP -44.09

H-bond Donors 165.0

H-bond Acceptors 159.0

Rotatable Bonds 362.0

Heavy Atoms 763.0

Ring Count 17.0

Amide Bonds 99.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0045110 VERIFIED: NO

Provenance & Taxonomy

OrganismLynx pardinus [Animal]

FamilyDefensin

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence