Peptide Database

Peptide NamePolytheonamide B (Proteusin)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length145 amino acids

Chemical FormulaC657H1056N198O225S3

DescriptionStandard

        MADSDNTPTSRKDFETAIIAKAWKDPEYLRRLRSNPREVLQEELEALHPGAQLPDDLGISIHEEDENHVHLVMPRHPQNVSDQTLTDDDLDQAAGGTGIGVVVAVVAGAVANTGAGVNQVAGGNINVVGNINVNANVSVNMNQTT
    

Molecular Weight15424.80 Da

Isoelectric Point (pI)4.53

Net Charge (pH 7.0)-12.03

Net Charge (pH 7.4) -12.53

Charge Density (pH 7.0) -0.0830

GRAVY Index-0.38

Hydrophobic Moment 0.73

Boman Index0.01

Instability Index36.87

Aliphatic Index 90.07

Aromaticity 0.0207

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6812.71

LogP -84.49

H-bond Donors 224.0

H-bond Acceptors 221.0

Rotatable Bonds 509.0

Heavy Atoms 1083.0

Ring Count 16.0

Amide Bonds 165.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0009616 VERIFIED: YES

Provenance & Taxonomy

OrganismBacterium symbiont subsp. Theonella swinhoei [Bacterium]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-positive Non-hemolytic

TargetGram-positive bacteria