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MYP_144731
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Basic Information
Putative endonuclease and reverse transcriptase-like protein (291-303)[Q3K,K5V,W7K]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
13 amino acids
C72H135N19O14
Standard
Sequence
GLKKVIKLLRPLL
Physicochemical Analysis
1490.96 Da
11.26
3.76
3.55
0.2890
0.73
0.80
0.10
12.74
202.31
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
543.69
-0.06
19.0
18.0
53.0
105.0
1.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0065038 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli ATCC 25922
64 μM
MIC
PMID33063186 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33063186/
RECORD: Rec_0111137 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Acinetobacter baumannii
32 μM
MIC
PMID33063186 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33063186/
RECORD: Rec_0128806 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human erythrocytes
<10 % Hemolysis
Hemolysis
PMID33063186 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33063186/
RECORD: Rec_0215635 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
Tumor cells: A549
50 μM
CC50
PMID33063186 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33063186/
RECORD: Rec_0248948 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Human lung carcinoma A549
50-60 % Cytotoxicity
Cytotoxicity
PMID33063186 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33063186/
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