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MYP_144725
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Basic Information
Pandinin-2 (Pin2; Arthropods, animals)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Insecticidal/Pest control ▸ Insecticidal activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
24 amino acids
C126H195N29O31
Standard
Sequence
FWGALAKGALKLIPSLFSSFSKKD
Physicochemical Analysis
2612.07 Da
10.00
2.76
2.55
0.1150
0.33
0.56
0.22
2.42
93.75
0.1667
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
961.92
-5.98
34.0
34.0
86.0
186.0
6.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0046223 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Guinea-pig erythrocytes
6 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/15328050/ PMID15328050 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15328050/
RECORD: Rec_0074017 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Guinea-pig erythrocytes
12.5 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/15328050/ PMID15328050 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15328050/
RECORD: Rec_0076076 VERIFIED: YES
Provenance & Taxonomy
Pandinus imperator [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
Enterococcus faecalis
2.4 μM
MIC
PMID11563967;15328050;15298871 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11563967/
RECORD: Rec_0077436 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Guinea-pig erythrocytes
50 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/14637016/ PMID14637016 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/14637016/
RECORD: Rec_0098586 VERIFIED: YES
Provenance & Taxonomy
Pandinus imperator [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
Staphylococcus epidermidis
4.8 μM
MIC
PMID11563967;15328050;15298871 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11563967/
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