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MYP_144725
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Basic Information
Pandinin-2 (Pin2; Arthropods, animals)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Insecticidal/Pest control ▸ Insecticidal activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
24 amino acids
C126H195N29O31
Standard
Sequence
FWGALAKGALKLIPSLFSSFSKKD
Physicochemical Analysis
2612.07 Da
10.00
2.76
2.55
0.1150
0.33
0.56
0.22
2.42
93.75
0.1667
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
961.92
-5.98
34.0
34.0
86.0
186.0
6.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0346665 VERIFIED: YES
Provenance & Taxonomy
Pandinus imperator [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
PMID11563967;15328050;15298871 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11563967/
RECORD: Rec_0347956 VERIFIED: YES
Provenance & Taxonomy
Pandinus imperator [Animal]
Natural peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antimycobacterial
Mycobacterium tuberculosis H37Rv
8.6 μM
MIC
PMID25019413 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25019413/
RECORD: Rec_0365858 VERIFIED: YES
Provenance & Taxonomy
Pandinus imperator [Animal]
NDBP
Structure & Mods
non-disulfide-bridged amphipathic peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic
Enterococcus faecalis
PMID11563967;15328050;23093034;16036557;24184590;15298871 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11563967/
RECORD: Rec_0372777 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
RECORD: Rec_0375139 VERIFIED: YES
Provenance & Taxonomy
Pandinus imperator [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Candida albicans
19.1 μM
MIC
PMID11563967 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11563967/
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