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MYP_144725
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Basic Information
Pandinin-2 (Pin2; Arthropods, animals)
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Insecticidal/Pest control ▸ Insecticidal activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
24 amino acids
C126H195N29O31
Standard
Sequence
FWGALAKGALKLIPSLFSSFSKKD
Physicochemical Analysis
2612.07 Da
10.00
2.76
2.55
0.1150
0.33
0.56
0.22
2.42
93.75
0.1667
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
961.92
-5.98
34.0
34.0
86.0
186.0
6.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0002846 VERIFIED: YES
Provenance & Taxonomy
Pandinus imperator [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
Bacillus subtilis
4.8 μM
MIC
PMID11563967;15328050;15298871 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11563967/
RECORD: Rec_0014417 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
Guinea-pig erythrocytes
25 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/15328050/ PMID15328050 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15328050/
RECORD: Rec_0017961 VERIFIED: YES
Provenance & Taxonomy
Pandinus imperator [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Pseudomonas aeruginosa
38.2 μM
MIC
PaperCharacterization of unique amphipathic antimicrobial peptides from venom of the scorpion Pandinus imperator
RECORD: Rec_0021776 VERIFIED: YES
Provenance & Taxonomy
Pandinus imperator [Animal]
Pandinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PaperBiochem J. 2001 Oct 1;359(Pt 1):35-45. | http://www.ncbi.nlm.nih.gov/pubmed/11563967 PMID11563967 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11563967/
RECORD: Rec_0025510 VERIFIED: YES
Provenance & Taxonomy
Pandinus imperator [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
2.4 μM
MIC
PMID11563967 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11563967/
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