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MYP_144706
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Basic Information
Cn-AMP1
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
9 amino acids
C34H61N13O12S
Standard
Sequence
SVAGRAQGM
Physicochemical Analysis
875.99 Da
9.47
0.46
0.25
0.0511
0.01
0.24
0.04
8.89
54.44
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
421.34
-6.49
15.0
14.0
29.0
60.0
0.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0293069 VERIFIED: YES
Provenance & Taxonomy
Cocos nucifera [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antibacterial Anti-Gram-negative
Escherichia coli
82 μg/mL
MIC
PaperPubMed PMID 19111587 | Silva et al. 2012 | Santana MJ et al., 2015 PMID19111587 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19111587/
RECORD: Rec_0329951 VERIFIED: YES
Provenance & Taxonomy
Cocos nucifera [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Xanthonomas axonopodis pv. vesicatoria
50 μM
MIC
PMID30508634 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30508634/
RECORD: Rec_0331166 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Antibacterial Antimicrobial Antifungal Anti-Gram-positive Anti-Gram-negative
PaperCAMP: Collection of sequences and structures of antimicrobial peptides PMID24265220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24265220/
RECORD: Rec_0366482 VERIFIED: YES
Provenance & Taxonomy
Not found [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Klebsiella pneumonia ATCC 10031
500 μM
MIC
Paper基于短链抗菌肽Cn-AMP1的拼接肽合成及抗菌活性研究; Study on synthesis and antibacterial activity of splicing peptides based on short chain antibacterial peptide Cn-AMP1. [J].齐齐哈尔医学院学报,2023,44(23):2208-2211. DOI:10.13819/j.issn.2096-708X.2021.05.001. Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?dataset=General&id=DRAMP37221
RECORD: Rec_0373760 VERIFIED: YES
Provenance & Taxonomy
Not found [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Shigella baumannii ATCC 9027
500 μM
MIC
Paper基于短链抗菌肽Cn-AMP1的拼接肽合成及抗菌活性研究; Study on synthesis and antibacterial activity of splicing peptides based on short chain antibacterial peptide Cn-AMP1. [J].齐齐哈尔医学院学报,2023,44(23):2208-2211. DOI:10.13819/j.issn.2096-708X.2021.05.001. Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?dataset=General&id=DRAMP37221
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