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MYP_144706
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Basic Information
Cn-AMP1
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
9 amino acids
C34H61N13O12S
Standard
Sequence
SVAGRAQGM
Physicochemical Analysis
875.99 Da
9.47
0.46
0.25
0.0511
0.01
0.24
0.04
8.89
54.44
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
421.34
-6.49
15.0
14.0
29.0
60.0
0.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0202395 VERIFIED: YES
Provenance & Taxonomy
Cocos nucifera [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
80 μg/mL
MIC
PMID19111587 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19111587/
RECORD: Rec_0210792 VERIFIED: YES
Provenance & Taxonomy
Cocos nucifera [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Pseudomonas syringae pv. syringae
50 μM
MIC
PMID30508634 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30508634/
RECORD: Rec_0216159 VERIFIED: YES
Provenance & Taxonomy
Cocos nucifera [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal Antibacterial Anti-Gram-positive
Staphylococcus aureus
80 μg/mL
MIC
PaperPubMed PMID 19111587 | Silva et al. 2012 | Santana MJ et al., 2015 PMID19111587 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19111587/
RECORD: Rec_0230462 VERIFIED: YES
Provenance & Taxonomy
Cocos nucifera [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Erwinia amylovora
50 μM
MIC
PMID30508634 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30508634/
RECORD: Rec_0234867 VERIFIED: YES
Provenance & Taxonomy
Cocos nucifera [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Escherichia coli
PMID19111587 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19111587/
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