Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length56 amino acids

Chemical FormulaC300H461N73O72S8

DescriptionStandard

        MKIPVFLFVLFFFLAPLPPVKCAMTDTYSCFVMRGKCRHECHDFEKPIGVCTKLNQ
    

Molecular Weight6498.84 Da

Isoelectric Point (pI)8.72

Net Charge (pH 7.0)2.63

Net Charge (pH 7.4) 2.22

Charge Density (pH 7.0) 0.0469

GRAVY Index0.38

Hydrophobic Moment 0.50

Boman Index0.17

Instability Index40.09

Aliphatic Index 78.21

Aromaticity 0.1429

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2267.66

LogP -11.89

H-bond Donors 81.0

H-bond Acceptors 85.0

Rotatable Bonds 206.0

Heavy Atoms 453.0

Ring Count 15.0

Amide Bonds 57.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0200934 VERIFIED: NO

Provenance & Taxonomy

OrganismAotus nancymaae [Animal]

FamilyDefensin

Tax ID37293

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence