Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length151 amino acids

Chemical FormulaC743H1166N214O214S7

DescriptionStandard

        MPKVQFTKRKETSQIFVHCSATKPPMDIGVREIAQWHKEQGWLAIGYHFVIRRDGTVEAGRDQDAVGSHVKGYNSTSVGVCLVGGIDAKGNPEANFTPAQMQALRSLLVELKVQYAGAVLMAHHDVAPKACPSFDLKRWWEKNELVTSDRG
    

Molecular Weight16744.97 Da

Isoelectric Point (pI)8.81

Net Charge (pH 7.0)3.01

Net Charge (pH 7.4) 2.41

Charge Density (pH 7.0) 0.0199

GRAVY Index-0.35

Hydrophobic Moment 0.65

Boman Index-0.01

Instability Index40.18

Aliphatic Index 76.82

Aromaticity 0.0795

Extinction Coeff. Reduced 26470.00

Extinction Coeff. Oxidized 26595.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6861.47

LogP -67.30

H-bond Donors 239.0

H-bond Acceptors 230.0

Rotatable Bonds 553.0

Heavy Atoms 1178.0

Ring Count 29.0

Amide Bonds 162.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0216634 VERIFIED: NO

Provenance & Taxonomy

OrganismKlebsiella phage NL_ZS_2 [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic