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MYP_144655
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Basic Information
Dermaseptin-AC4 [A10L,A17V,L18A,V25A], DRP-AC4b
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
27 amino acids
C120H201N35O35S
Standard
Sequence
SLWGKLKEMLAAAGKAVANAVNGLANQ
Physicochemical Analysis
2726.16 Da
9.70
1.46
1.25
0.0541
0.22
0.53
0.19
-6.38
105.19
0.0370
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1143.66
-11.85
38.0
38.0
93.0
191.0
2.0
30.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0014392 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans NCTC 1467
64 μM
MIC
PMID32397600 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32397600/
RECORD: Rec_0046210 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Klebsiella pneumoniae ATCC 43816
64 μM
MBC
PMID32397600 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32397600/
RECORD: Rec_0058505 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Enterococcus faecalis NCTC 12697
32 μM
MBC
PMID32397600 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32397600/
RECORD: Rec_0063079 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Enterococcus faecalis NCTC 12697
32 μM
MIC
PMID32397600 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32397600/
RECORD: Rec_0065280 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Horse erythrocytes
10 % Hemolysis
Hemolysis
PMID32397600 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32397600/
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