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MYP_144626
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Basic Information
N15k
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
16 amino acids
C74H136N18O20
Standard
Sequence
ILGKLLSTAAGLLSKL
Physicochemical Analysis
1597.98 Da
10.00
1.76
1.55
0.1099
1.25
0.40
0.41
5.49
183.12
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
612.55
-4.08
22.0
22.0
56.0
112.0
0.0
15.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0362012 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
human red blood cells
310 μM
HC50
PMID22965637;22392897 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22965637/
RECORD: Rec_0370980 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Alyteserin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D or modified amino-acid peptide [Mixed]
None
Amidation
k=D-Lys
Bio-Activity Profile
Antimicrobial Anticancer
A549
75 μM
LC50
PMID22965637 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22965637/
RECORD: Rec_0381444 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer Cytotoxic
Human hepatocellular carcinoma HepG2
17 μM
LC50
PMID22965637;22392897 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22965637/
RECORD: Rec_0405587 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Klebsiella pneumoniae ATCC 700603
128 μM
MIC
PMID22965637;22392897 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22965637/
RECORD: Rec_0424119 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Alyteserin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D or modified amino-acid peptide [Mixed]
None
Amidation
k=D-Lys
Bio-Activity Profile
Antimicrobial Anticancer
MDA-MB-231
80 μM
LC50
PMID22965637 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22965637/
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