Peptide Database

Peptide NameGlia-alpha2 18-mer (p71 p89; E79)

Function Ontology

Immunology ▸ Immunomodulation ▸ Celiac-immunogenic

Standard StatusStandard

Sequence Length18 amino acids

Chemical FormulaC103H143N23O28

DescriptionStandard

        QPQPYPQPELPYPQPQPF
    

Molecular Weight2151.37 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-1.24

Net Charge (pH 7.4) -1.45

Charge Density (pH 7.0) -0.0688

GRAVY Index-1.66

Hydrophobic Moment 0.21

Boman Index-0.07

Instability Index150.51

Aliphatic Index 21.67

Aromaticity 0.1667

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 780.91

LogP -4.93

H-bond Donors 19.0

H-bond Acceptors 27.0

Rotatable Bonds 53.0

Heavy Atoms 154.0

Ring Count 11.0

Amide Bonds 22.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0041369 VERIFIED: YES

Provenance & Taxonomy

OrganismTriticum aestivum [Plant]

FamilyGliadin

Tax ID4565

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsDeamidation; Reported substitutions/positions: E79

Bio-Activity Profile

Function

Celiac-immunogenic

TargetHuman intestinal T cells / HLA-DQ2

MethodT-cell proliferation assay

RECORD: Rec_0342639 VERIFIED: YES