Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length80 amino acids

Chemical FormulaC415H680N114O108S9

DescriptionStandard

        MNLLMLAFTICGSLTLVAKANWKIQRCWEKDIGHCRKRCFQNERYKLLCKNKLTCCIPITAQLSTPKPPPRVIYIEDITV
    

Molecular Weight9283.12 Da

Isoelectric Point (pI)9.40

Net Charge (pH 7.0)7.52

Net Charge (pH 7.4) 7.13

Charge Density (pH 7.0) 0.0940

GRAVY Index-0.01

Hydrophobic Moment 0.61

Boman Index0.00

Instability Index24.92

Aliphatic Index 98.75

Aromaticity 0.0750

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3586.62

LogP -27.41

H-bond Donors 131.0

H-bond Acceptors 126.0

Rotatable Bonds 308.0

Heavy Atoms 646.0

Ring Count 14.0

Amide Bonds 86.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0160895 VERIFIED: NO

Provenance & Taxonomy

OrganismLoxodonta africana [Animal]

FamilyDefensin

Tax ID9785

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence