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MYP_144577
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ Xanthine oxidase inhibition
Metabolic ▸ Uric acid metabolism ▸ Hypouricemic activity
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
4 amino acids
C19H34N4O5S
Standard
Sequence
ALPM
Physicochemical Analysis
430.56 Da
5.57
-0.20
-0.39
-0.0510
1.48
0.20
0.61
36.80
122.50
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
141.83
0.18
4.0
6.0
11.0
29.0
1.0
3.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0014704 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
928 μM
IC50
PaperISOLATION AND CHARACTERIZATION OF PEPTIDES WITH ANTIHYPERTENSIVE ACTIVITY IN FOODSTUFFS. PMID24915368 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24915368/
RECORD: Rec_0047084 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antihypertensive
PaperAHTPDB: a comprehensive platform for analysis and presentation of antihypertensive peptides PMID25392419 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25392419/
RECORD: Rec_0053805 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hypouricemic Xanthine Oxidase Inhibitor
5.01
IC50
PaperQi X., Chen H., Guan K., Sun Y., Wang R., Li Q., Ma Y.. Novel xanthine oxidase inhibitory peptides derived from whey protein: identification, in vitro inhibition mechanism and in vivo activity validation. Bioorg. Chem., 128, 106097, 2022.
RECORD: Rec_0060342 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
Spontaneously hypertensive rat (SHR)
21.4 mmHg
SBP decrease
PaperISOLATION AND CHARACTERIZATION OF PEPTIDES WITH ANTIHYPERTENSIVE ACTIVITY IN FOODSTUFFS. PMID24915368 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24915368/
RECORD: Rec_0064045 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Lactosin
9913
Structure & Mods
proteolytic peptide fragment [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
928 μM
IC50
PaperStructural Analysis of a New Anti-Hypertensive Peptide (β-Lactosin B) Isolated from a Commercial Whey Product PMID15328207 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15328207/
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