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MYP_144551
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Basic Information
Epicidin 280
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
30 amino acids
C137H236N42O41S3
Standard
Sequence
SLGPAIKATRQVCPKATRFVTVSCKKSDCQ
Physicochemical Analysis
3223.79 Da
9.75
4.43
4.17
0.1476
-0.22
0.68
-0.13
29.11
65.00
0.0333
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1362.38
-17.58
51.0
49.0
107.0
223.0
3.0
31.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0029092 VERIFIED: YES
Provenance & Taxonomy
Staphylococcus epidermidis [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
S.simulans 22
0.304 μg/mL
MIC
PMID9726851 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9726851/
RECORD: Rec_0078446 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct based on Staphylococcus epidermidis [Synthetic]
Bacteriocin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperIsolation, characterization, and heterologous expression of the novel lantibiotic epicidin 280 and analysis of its biosynthetic gene cluster
RECORD: Rec_0119944 VERIFIED: YES
Provenance & Taxonomy
Staphylococcus epidermidis [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
S.epidermidis5
70 μg/mL
MIC
PMID9726851 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9726851/
RECORD: Rec_0123890 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
PaperBACTIBASE second release: a database and tool platform for bacteriocin characterization PMID20105292 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20105292/
RECORD: Rec_0177888 VERIFIED: YES
Provenance & Taxonomy
Staphylococcus epidermidis [Bacterium]
Bacteriocin
1282
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Oxypropionylation
There are possible lanthionine(Lan)/3-methyllanthionine(Me-Lan) structure association between Thr9 and Cys13, Thr21 and Cys24, Ser23 and Cys29
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Micrococcus luteus ATCC4698
9.7 μg/mL
MIC
PMID9726851 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9726851/
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