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MYP_144545
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Basic Information
Cliotide T21 (Cyclotide cT21)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
28 amino acids
C131H204N38O39S6
Standard
Sequence
DLQCAETCVHSPCIGPCYCKHGLICYRN
Physicochemical Analysis
3127.64 Da
6.87
-0.12
-0.52
-0.0044
0.03
0.32
0.06
20.87
69.64
0.0714
2980.00
3355.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1218.42
-12.72
47.0
47.0
96.0
214.0
6.0
29.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0045751 VERIFIED: NO
Provenance & Taxonomy
Clitoria ternatea [Plant]
Cyclotide
43366
Structure & Mods
backbone-cyclized cyclotide scaffold [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperCliotide T21 (Cyclotide cT21) Evidence URLhttps://www.uniprot.org/uniprotkb/C0HJS8/entry
RECORD: Rec_0124218 VERIFIED: YES
Provenance & Taxonomy
Clitoria ternatea [Plant]
Cyclotide
43366
Structure & Mods
head-to-tail cyclic peptide scaffold [Cyclic]
canonical L-amino-acid peptide [L]
Cysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family
Bio-Activity Profile
Antimicrobial Antibacterial
Caenorhabditis elegans
PaperImmunostimulating and Gram-negative-specific antibacterial cyclotides from the butterfly pea (Clitoria ternatea) PMID27007913 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27007913/
RECORD: Rec_0160824 VERIFIED: NO
Provenance & Taxonomy
Clitoria ternatea [Plant]
Cyclotide
Structure & Mods
backbone-cyclized peptide [Cyclic]
canonical L-amino-acid peptide [L]
4-17; 8-19; 13-25
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0236146 VERIFIED: YES
Provenance & Taxonomy
Clitoria ternatea [Plant]
Cyclotide
43366
Structure & Mods
head-to-tail cyclic peptide scaffold [Cyclic]
canonical L-amino-acid peptide [L]
Cysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
PaperImmunostimulating and Gram-negative-specific antibacterial cyclotides from the butterfly pea (Clitoria ternatea) PMID27007913 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27007913/
RECORD: Rec_0379342 VERIFIED: YES
Provenance & Taxonomy
Clitoria ternatea [Plant]
Cyclotide
43366
Structure & Mods
head-to-tail cyclic peptide scaffold [Cyclic]
canonical L-amino-acid peptide [L]
Cysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
100 μM
MIC
PaperImmunostimulating and Gram-negative-specific antibacterial cyclotides from the butterfly pea (Clitoria ternatea) PMID27007913 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27007913/