Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length122 amino acids

Chemical FormulaC611H994N170O180S11

DescriptionStandard

        MNLLMLAFTICGSLTLVAKFSTAGWEIQRCWENDIGHCRKRCLQNERYKLLCKNKLTCCIPITAQSFTRRPPPRAIDTEDITVTMETYPPLTMDDFITFKISSPSQAKTTKKTSSESTVRIR
    

Molecular Weight13954.18 Da

Isoelectric Point (pI)9.23

Net Charge (pH 7.0)6.53

Net Charge (pH 7.4) 6.13

Charge Density (pH 7.0) 0.0535

GRAVY Index-0.29

Hydrophobic Moment 0.56

Boman Index-0.07

Instability Index48.84

Aliphatic Index 75.98

Aromaticity 0.0738

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5675.66

LogP -58.77

H-bond Donors 208.0

H-bond Acceptors 199.0

Rotatable Bonds 463.0

Heavy Atoms 972.0

Ring Count 19.0

Amide Bonds 129.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0307190 VERIFIED: NO

Provenance & Taxonomy

OrganismTrichechus manatus latirostris [Bacterium]

FamilyDefensin

Tax ID127582

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence