MYP_144535
Basic Information
Temporin-SHa G10K analog
Anticancer
Antimicrobial
Standard
13 amino acids
C71H117N15O15S
Standard
Sequence
FLSGIVGMLKKLF
Physicochemical Analysis
1452.84 Da
10.00
1.76
1.55
0.1352
1.40
0.51
0.50
-23.42
142.31
0.1538
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
484.79
-0.19
17.0
18.0
50.0
102.0
2.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0003829 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
APD analysis reveals that this sequence is similar (92.31%) to temporin-SHa L: 23%, F=G=K: 15%. Chemical modification: C-terminal amidation
Bio-Activity Profile
Antimicrobial Anticancer
Anticancer: Breast Cancer MCF-7, Liver Cancer HepG-2, Ovarian Cancer A2780, Pancreatic Cancer MiaPaCa-2, Prostate Cancer PC-3, Skin Cancer MNT-1, Lung Cancer A549
11.7-64 μM
IC50
RECORD: Rec_0006932 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
APD analysis reveals that this sequence is similar (92.31%) to temporin-SHa L: 23%, F=G=K: 15%. Chemical modification: C-terminal amidation
Bio-Activity Profile
Antimicrobial Anticancer
Staphylococcus aureus ATCC 6538
3.12 μM
MIC
RECORD: Rec_0011336 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
APD analysis reveals that this sequence is similar (92.31%) to temporin-SHa L: 23%, F=G=K: 15%. Chemical modification: C-terminal amidation
Bio-Activity Profile
Antimicrobial Anticancer
E. faecium DSM 20477
6.25 μM
MIC
RECORD: Rec_0046764 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
APD analysis reveals that this sequence is similar (92.31%) to temporin-SHa L: 23%, F=G=K: 15%. Chemical modification: C-terminal amidation
Bio-Activity Profile
Antimicrobial Anticancer
Bacillus subtilis ATCC 6633
3.12 μM
MIC
RECORD: Rec_0086691 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
APD analysis reveals that this sequence is similar (92.31%) to temporin-SHa L: 23%, F=G=K: 15%. Chemical modification: C-terminal amidation
Bio-Activity Profile
Antimicrobial Anticancer
Escherichia coli ATCC 8739
25 μM
MIC
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