Peptide Database

Peptide NameAmphipathic peptide CT1 (StCT1) (Non-disulfide-bridged peptide 4.8) (NDBP-4.8) (Non-disulfide-bridged peptide 5.16) (NDBP-5.16)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length74 amino acids

Chemical FormulaC386H613N99O110S5

DescriptionStandard

        MKTQIVILFISMIMLQMFVQIEGGFWGSLWEGVKSVVGKRGLRNLDDLDDLDLDHLFDSDVSDADLRLLKQMFR
    

Molecular Weight8560.92 Da

Isoelectric Point (pI)4.61

Net Charge (pH 7.0)-4.40

Net Charge (pH 7.4) -4.68

Charge Density (pH 7.0) -0.0595

GRAVY Index0.18

Hydrophobic Moment 0.83

Boman Index0.11

Instability Index36.73

Aliphatic Index 114.46

Aromaticity 0.0946

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3383.99

LogP -22.97

H-bond Donors 117.0

H-bond Acceptors 112.0

Rotatable Bonds 296.0

Heavy Atoms 600.0

Ring Count 10.0

Amide Bonds 78.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0053991 VERIFIED: YES

Provenance & Taxonomy

OrganismScorpiops tibetanus [Animal]

FamilyNDBP

Structure & Mods

Confignon-disulfide-bridged amphipathic peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Anti-Gram-positive Cytolytic Non-hemolytic

TargetMicrococcus luteus

RECORD: Rec_0066844 VERIFIED: YES