Peptide Database

Peptide NameCardiodilatin-related peptide

Function Ontology

Cardiovascular

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length30 amino acids

Chemical FormulaC154H240N38O51S2

DescriptionStandard

        NPMYNVVSNADLVDFKNLLDHLEEKMPLED
    

Molecular Weight3503.91 Da

Isoelectric Point (pI)4.26

Net Charge (pH 7.0)-5.14

Net Charge (pH 7.4) -5.41

Charge Density (pH 7.0) -0.1713

GRAVY Index-0.49

Hydrophobic Moment 0.59

Boman Index-0.01

Instability Index41.52

Aliphatic Index 97.33

Aromaticity 0.0667

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1444.28

LogP -11.40

H-bond Donors 45.0

H-bond Acceptors 49.0

Rotatable Bonds 116.0

Heavy Atoms 245.0

Ring Count 5.0

Amide Bonds 33.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0198992 VERIFIED: NO

Provenance & Taxonomy

OrganismCavia porcellus [Animal]

FamilyCardiodilatin-related peptide

Tax ID10141

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Vasoactive Vasodilator Cardiovascular Metabolic regulation Physiological regulation Reproductive regulator Receptor modulation ACE inhibitory

Half-LifeMammalian: 1.4 hour; Yeast: 3 min; E. coli: >10 hour

RECORD: Rec_0295800 VERIFIED: NO

Provenance & Taxonomy

OrganismCavia porcellus [Animal]

FamilyCardiodilatin-related peptide

Tax ID10141

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Vasoactive Vasodilator Cardiovascular Metabolic regulation Physiological regulation Reproductive regulator Receptor modulation ACE inhibitory

Targetadipose tissue

Half-LifeMammalian: 1.4 hour; Yeast: 3 min; E. coli: >10 hour

RECORD: Rec_0375702 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0401968 VERIFIED: NO

Provenance & Taxonomy

OrganismCavia porcellus [Animal]

FamilyNatriuretic peptide

Tax ID10141

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Cardiovascular