Peptide Database

Peptide NameAntimicrobial peptide lumbricin-PG (Lumbricin-PG)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Standard StatusStandard

Sequence Length73 amino acids

Chemical FormulaC387H581N101O110S3

DescriptionStandard

        MLLTISDFLFLSLTFSRYARMRDSRPWSDRKNNYSGPQFTYPPEKAPPEKLIKWNNEGSPIFEMPAEGGHIEP
    

Molecular Weight8504.56 Da

Isoelectric Point (pI)6.56

Net Charge (pH 7.0)-0.40

Net Charge (pH 7.4) -0.69

Charge Density (pH 7.0) -0.0055

GRAVY Index-0.74

Hydrophobic Moment 0.53

Boman Index-0.06

Instability Index67.21

Aliphatic Index 57.53

Aromaticity 0.1370

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3367.39

LogP -29.06

H-bond Donors 114.0

H-bond Acceptors 114.0

Rotatable Bonds 268.0

Heavy Atoms 601.0

Ring Count 22.0

Amide Bonds 77.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0153240 VERIFIED: YES

Provenance & Taxonomy

OrganismMetaphire guillelmi [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic

TargetStaphylococcus aureus

RECORD: Rec_0297565 VERIFIED: YES

Provenance & Taxonomy

OrganismMetaphire guillelmi [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic

TargetEscherichia coli

RECORD: Rec_0375972 VERIFIED: YES

Provenance & Taxonomy

OrganismMetaphire guillelmi [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic

TargetCandida albicans

RECORD: Rec_0411631 VERIFIED: YES

Provenance & Taxonomy

OrganismMetaphire guillelmi [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic

TargetPseudomonas aeruginosa