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MYP_144481
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Basic Information
Decoralin [AC11]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
11 amino acids
C67H117N17O15
Standard
Sequence
QLLQLIRKLIY
Physicochemical Analysis
1400.75 Da
9.99
1.76
1.55
0.1598
0.68
0.69
0.14
31.01
212.73
0.0909
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
548.65
-0.61
19.0
17.0
49.0
99.0
1.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0033065 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
HDMEC
349±1 μM
EC50
PaperMultidimensional Design of Anticancer Peptides. Angew Chem Int Ed Engl. 2015 Aug 24;54(35):10370-10374. doi: 10.1002/anie.201504018. PMID: 26119906. PMID26119906 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26119906/
RECORD: Rec_0041662 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
Jurkat
58±1 μM
EC50
PaperMultidimensional Design of Anticancer Peptides. Angew Chem Int Ed Engl. 2015 Aug 24;54(35):10370-10374. doi: 10.1002/anie.201504018. PMID: 26119906. PMID26119906 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26119906/
RECORD: Rec_0126579 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PaperMultidimensional Design of Anticancer Peptides. Angew Chem Int Ed Engl. 2015 Aug 24;54(35):10370-10374. doi: 10.1002/anie.201504018. PMID: 26119906. PMID26119906 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26119906/
RECORD: Rec_0290149 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
A549
61±1 μM
EC50
PaperMultidimensional Design of Anticancer Peptides. Angew Chem Int Ed Engl. 2015 Aug 24;54(35):10370-10374. doi: 10.1002/anie.201504018. PMID: 26119906. PMID26119906 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26119906/
RECORD: Rec_0339294 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
MCF-7
50-100 μM
EC50
PaperMultidimensional Design of Anticancer Peptides. Angew Chem Int Ed Engl. 2015 Aug 24;54(35):10370-10374. doi: 10.1002/anie.201504018. PMID: 26119906. PMID26119906 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26119906/
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