Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length196 amino acids

Chemical FormulaC984H1555N269O262S10

DescriptionStandard

        PNTPPMAHEPMLLLAVTEFVANSAAFTYFTAGALRRNISSDMVPRKFPLQLRTKSMEVFSPQLQERYPDQPMELHLWARRQPLLSCHPDALHGTLFSSAEAFVVLPNATRVPAFLLNIDANVTGKPIITRNRLGGTVRLTGLVPDPDLAWSPLPALCCAQGLPVPQVKRLETLLKFGLWLFGVPRANSKCCPHPIP
    

Molecular Weight21666.17 Da

Isoelectric Point (pI)9.38

Net Charge (pH 7.0)6.36

Net Charge (pH 7.4) 5.95

Charge Density (pH 7.0) 0.0325

GRAVY Index0.03

Hydrophobic Moment 0.55

Boman Index0.10

Instability Index53.56

Aliphatic Index 94.08

Aromaticity 0.0765

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19730.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8290.02

LogP -99.87

H-bond Donors 284.0

H-bond Acceptors 283.0

Rotatable Bonds 675.0

Heavy Atoms 1525.0

Ring Count 47.0

Amide Bonds 210.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0415608 VERIFIED: NO

Provenance & Taxonomy

OrganismMelanocharis versteri [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria