Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length81 amino acids

Chemical FormulaC419H653N117O124S8

DescriptionStandard

        KCWDDMGHCRRRCLDNERYKLLCKNKVSCCIPIRKSYDDTPRPLPPLIPIWHITIDVGDWIPVSPGLNDEMTFDDKEHEET
    

Molecular Weight9569.90 Da

Isoelectric Point (pI)5.50

Net Charge (pH 7.0)-3.02

Net Charge (pH 7.4) -3.49

Charge Density (pH 7.0) -0.0373

GRAVY Index-0.73

Hydrophobic Moment 0.65

Boman Index-0.15

Instability Index59.29

Aliphatic Index 73.33

Aromaticity 0.0741

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3852.77

LogP -32.46

H-bond Donors 137.0

H-bond Acceptors 132.0

Rotatable Bonds 308.0

Heavy Atoms 668.0

Ring Count 20.0

Amide Bonds 83.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0176851 VERIFIED: NO

Provenance & Taxonomy

OrganismHeterocephalus glaber [Animal]

FamilyDefensin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0308971 VERIFIED: NO